Luca Longo is an Italian computer scientist specializing in explainable artificial intelligence, deep learning, and argumentation theory, with research in the areas of human performance modeling and neural engineering. He conducts fundamental research on computational models of cognitive load and brain–computer interfaces. Longo is a professor at University College Cork in Ireland, where he currently leads the Artificial Intelligence and Cognitive Load research labs aimed at expanding the boundaries of artificial intelligence and bridging the gap between machines and humans. He is also connected with Trinity College Dublin and the University of Insubria. Longo is the founder and general chair of the World Conference on Explainable Artificial Intelligence, as well as the founder of the first Centre of Explainable Artificial Intelligence in Ireland. He serves as an editor of books and journals with Springer Publishing and Frontiers Media. Additionally, he is a public speaker disseminating technical knowledge to the wider public and contributing to the non-profit organization TED "ideas worth spreading".

Originally from Varese, Longo began his academic journey with a bachelor's and a master's degree in Computer Science from the University of Insubria. A polymath, he went on to earn a doctorate in Artificial Intelligence and a doctorate in Neuroscience at Trinity College Dublin, where he also obtained master's degrees in Health informatics and Statistics. Additionally, he earned two master's degrees in Pedagogy at Technological University Dublin, one in Scholarship of teaching and learning and one in Applied E-learning.

Prof. Longo is ranked among the top 2% of the world's most influential scientists, appearing in Stanford University's ranking of researchers from the Scopus database across all research areas using the c-score. He is the recipient of the 2023 "AI Person of the Year" award, organised by AI Ireland, a non-profit organisation focused on promoting artificial intelligence in Ireland. In 2025, his manifesto for Explainable artificial intelligence received the best paper award of the year in the Elsevier journal Information Fusion.

As an educator striving to empower education with the use of technology and artificial intelligence, Longo won the Teaching Hero Award in Ireland from the National Forum for Teaching and Learning in both 2016 and 2021 for inspiring students by creating motivating and stimulating learning environments that support the acquisition of skills and practical knowledge through the mastery of the Community of Inquiry in higher education. His approach to doctoral supervision led to a 2021 nomination for the award 'Outstanding Research Supervisor of the Year', widely recognised as the 'Oscars of higher education' organised by the leading higher education magazine Times Higher Education. These distinctions contributed to his conferral of the 2024 "Italiani nel mondo" award from Associazioni sportive sociali italiane.